clinical-trial — Hawaii Medical Journal

An elderly tailor meticulously works with fabric in a well-equipped sewing workshop, surrounded by threads and sewing machines.

Tecovirimat in the Treatment of Mpox: Clinical Efficacy and Therapeutic Implications

A comprehensive analysis of tecovirimat's clinical efficacy in mpox treatment demonstrates significant reduction in lesion resolution time and viral shedding duration. The findings establish tecovirimat as a viable therapeutic option for severe mpox infections requiring antiviral intervention.

By Dr. James Liu January 26, 2026

A hand in a red glove holding a laboratory flask against a neutral background.

Bimagrumab Plus Semaglutide for Obesity Management: Analysis of a Phase 2 Randomized Controlled Trial Demonstrating Enhanced Weight Reduction with Lean Mass Preservation

A phase 2 randomized controlled trial demonstrated that the combination of bimagrumab and semaglutide achieved superior weight reduction compared with semaglutide monotherapy while preserving lean muscle mass. The combination therapy resulted in a least squares mean weight loss of 17.8 kg versus 14.2 kg with semaglutide alone at 48 weeks.

By Dr. James Liu January 5, 2026